Penetrating Traumatic Brain Injury Triggers Dysregulation of Cathepsin B Protein Levels Independent of Cysteine Protease Activity in Brain and Cerebral Spinal Fluid

Cathepsin B (CatB), a lysosomal cysteine protease, is important to brain function and may have dual utility as a peripheral biomarker of moderate-severe traumatic brain injury (TBI). The present study determined levels of pro- and mature (mat) CatB protein as well as cysteine protease activity withi...

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Dades bibliogràfiques
Publicat a:J Neurotrauma
Autors principals: Boutté, Angela M., Hook, Vivian, Thangavelu, Bharani, Sarkis, George Anis, Abbatiello, Brittany N., Hook, Gregory, Jacobsen, J. Steven, Robertson, Claudia S., Gilsdorf, Janice, Yang, Zhihui, Wang, Kevin K.W., Shear, Deborah A.
Format: Artigo
Idioma:Inglês
Publicat: Mary Ann Liebert, Inc., publishers 2020
Matèries:
Original Articles
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7307674/
https://ncbi.nlm.nih.gov/pubmed/31973644
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/neu.2019.6537
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