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Mutation of an Influenza Virus Polymerase 3′ RNA Promoter Binding Site Inhibits Transcription Elongation

Influenza viruses encode a viral RNA-dependent RNA polymerase (FluPol), which is responsible for transcribing and replicating the negative-sense viral RNA (vRNA) genome. FluPol transcribes vRNA using a host-capped mRNA primer and replicates it by synthesizing a positive-sense cRNA intermediate, whic...

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Dades bibliogràfiques
Publicat a:J Virol
Autors principals: Walker, Alexander P., Sharps, Jane, Fodor, Ervin
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2020
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7307170/
https://ncbi.nlm.nih.gov/pubmed/32295915
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00498-20
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