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Mutation of an Influenza Virus Polymerase 3′ RNA Promoter Binding Site Inhibits Transcription Elongation
Influenza viruses encode a viral RNA-dependent RNA polymerase (FluPol), which is responsible for transcribing and replicating the negative-sense viral RNA (vRNA) genome. FluPol transcribes vRNA using a host-capped mRNA primer and replicates it by synthesizing a positive-sense cRNA intermediate, whic...
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| Publicado en: | J Virol |
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| Autores principales: | , , |
| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
American Society for Microbiology
2020
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7307170/ https://ncbi.nlm.nih.gov/pubmed/32295915 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00498-20 |
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