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The Surface-Exposed PA(51-72)-Loop of the Influenza A Virus Polymerase Is Required for Viral Genome Replication
The heterotrimeric influenza A virus RNA-dependent RNA polymerase complex, composed of PB1, PB2, and PA subunits, is responsible for transcribing and replicating the viral RNA genome. The N-terminal endonuclease domain of the PA subunit performs endonucleolytic cleavage of capped host RNAs to genera...
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| Publicado en: | J Virol |
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| Autores principales: | , , , |
| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
American Society for Microbiology
2018
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6069170/ https://ncbi.nlm.nih.gov/pubmed/29875249 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00687-18 |
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