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RNA-Free and Ribonucleoprotein-Associated Influenza Virus Polymerases Directly Bind the Serine-5-Phosphorylated Carboxyl-Terminal Domain of Host RNA Polymerase II

Influenza viruses subvert the transcriptional machinery of their hosts to synthesize their own viral mRNA. Ongoing transcription by cellular RNA polymerase II (Pol II) is required for viral mRNA synthesis. By a process known as cap snatching, the virus steals short 5′ capped RNA fragments from host...

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Detalhes bibliográficos
Publicado no:J Virol
Main Authors: Martínez-Alonso, Mónica, Hengrung, Narin, Fodor, Ervin
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4907247/
https://ncbi.nlm.nih.gov/pubmed/27099314
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00494-16
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