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RNA-Free and Ribonucleoprotein-Associated Influenza Virus Polymerases Directly Bind the Serine-5-Phosphorylated Carboxyl-Terminal Domain of Host RNA Polymerase II

Influenza viruses subvert the transcriptional machinery of their hosts to synthesize their own viral mRNA. Ongoing transcription by cellular RNA polymerase II (Pol II) is required for viral mRNA synthesis. By a process known as cap snatching, the virus steals short 5′ capped RNA fragments from host...

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Vydáno v:J Virol
Hlavní autoři: Martínez-Alonso, Mónica, Hengrung, Narin, Fodor, Ervin
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 2016
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4907247/
https://ncbi.nlm.nih.gov/pubmed/27099314
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00494-16
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