Cellular Gene Modulation of HIV-Infected CD4 T Cells in Response to Serial Treatment with the Histone Deacetylase Inhibitor Vorinostat

Histone deacetylase inhibitors (HDACi) are the most widely studied HIV latency-reversing agents (LRAs). The HDACi suberoylanilide hydroxamic acid (vorinostat [VOR]) has been employed in several clinical HIV latency reversal studies, as well as in vitro models of HIV latency, and has been shown to ef...

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Veröffentlicht in:J Virol
Hauptverfasser: Maxwell, Jill W., Falcinelli, Shane D., Nefedov, Alexey, Dorfmeier, Corin, Wu, Guoxin, Dewey, Morgan, Webber, Andrea L., Archin, Nancie M., Margolis, David M., Hazuda, Daria J., Barnard, Richard J. O., Howell, Bonnie J.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology 2020
Schlagworte:
Cellular Response to Infection
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7307144/
https://ncbi.nlm.nih.gov/pubmed/32295913
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00351-20
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