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Effect of SUMO-SIM Interaction on the ICP0-Mediated Degradation of PML Isoform II and Its Associated Proteins in Herpes Simplex Virus 1 Infection

ND10 nuclear bodies, as part of the intrinsic defenses, impose repression on incoming DNA. Infected cell protein 0 (ICP0), an E3 ubiquitin ligase of herpes simplex virus 1 (HSV-1), can derepress viral genes by degrading ND10 organizers to disrupt ND10. These events are part of the initial tug of war...

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Bibliografiske detaljer
Udgivet i:J Virol
Main Authors: Jan Fada, Behdokht, Kaadi, Elie, Samrat, Subodh Kumar, Zheng, Yi, Gu, Haidong
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2020
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7307090/
https://ncbi.nlm.nih.gov/pubmed/32295906
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00470-20
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