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A Tale of Two PMLs: Elements Regulating a Differential Substrate Recognition by the ICP0 E3 Ubiquitin Ligase of Herpes Simplex Virus 1

Infected cell protein 0 (ICP0) of herpes simplex virus 1 (HSV-1) is an α gene product required for viral replication at low multiplicities of infection. Upon entry, nuclear domain 10 (ND10) converges at the incoming DNA and represses viral gene expression. ICP0 contains a RING-type E3 ubiquitin liga...

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Detalhes bibliográficos
Publicado no:J Virol
Main Authors: Zheng, Yi, Samrat, Subodh Kumar, Gu, Haidong
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5110152/
https://ncbi.nlm.nih.gov/pubmed/27681131
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01636-16
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