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MHC-II alleles shape the CDR3 repertoires of conventional and regulatory naïve CD4(+) T cells
T cell maturation and activation depend upon T cell receptor (TCR) interactions with a wide variety of antigenic peptides displayed in a given major histocompatibility complex (MHC) context. Complementarity-determining region 3 (CDR3) is the most variable part of the TCRα and -β chains, which govern...
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| Publicado no: | Proc Natl Acad Sci U S A |
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| Main Authors: | , , , , , , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7306996/ https://ncbi.nlm.nih.gov/pubmed/32482872 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.2003170117 |
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