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The Changing Landscape of Naive T Cell Receptor Repertoire With Human Aging
Human aging is associated with a profound loss of thymus productivity, yet naïve T lymphocytes still maintain their numbers by division in the periphery for many years. The extent of such proliferation may depend on the cytokine environment, including IL-7 and T-cell receptor (TCR) “tonic” signaling...
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| Publicado no: | Front Immunol |
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| Main Authors: | , , , , , , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Frontiers Media S.A.
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6066563/ https://ncbi.nlm.nih.gov/pubmed/30087674 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2018.01618 |
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