Mitoribosome Defect in Hepatocellular Carcinoma Promotes an Aggressive Phenotype with Suppressed Immune Reaction

Mitochondrial ribosomes (mitoribosomes), the specialized translational machinery for mitochondrial genes, exclusively encode the subunits of the oxidative phosphorylation (OXPHOS) system. Although OXPHOS dysfunctions are associated with hepatic disorders including hepatocellular carcinoma (HCC), the...

Full description

Saved in:
Bibliographic Details
Published in:iScience
Main Authors: Kwon, So Mee, Lee, Young-Kyoung, Min, Seongki, Woo, Hyun Goo, Wang, Hee Jung, Yoon, Gyesoon
Format: Artigo
Language:Inglês
Published: Elsevier 2020
Subjects:
Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7306587/
https://ncbi.nlm.nih.gov/pubmed/32629612
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.isci.2020.101247
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items