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Mitoribosome Defect in Hepatocellular Carcinoma Promotes an Aggressive Phenotype with Suppressed Immune Reaction

Mitochondrial ribosomes (mitoribosomes), the specialized translational machinery for mitochondrial genes, exclusively encode the subunits of the oxidative phosphorylation (OXPHOS) system. Although OXPHOS dysfunctions are associated with hepatic disorders including hepatocellular carcinoma (HCC), the...

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Bibliografiske detaljer
Udgivet i:iScience
Main Authors: Kwon, So Mee, Lee, Young-Kyoung, Min, Seongki, Woo, Hyun Goo, Wang, Hee Jung, Yoon, Gyesoon
Format: Artigo
Sprog:Inglês
Udgivet: Elsevier 2020
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7306587/
https://ncbi.nlm.nih.gov/pubmed/32629612
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.isci.2020.101247
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