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Mitoribosome Defect in Hepatocellular Carcinoma Promotes an Aggressive Phenotype with Suppressed Immune Reaction

Mitochondrial ribosomes (mitoribosomes), the specialized translational machinery for mitochondrial genes, exclusively encode the subunits of the oxidative phosphorylation (OXPHOS) system. Although OXPHOS dysfunctions are associated with hepatic disorders including hepatocellular carcinoma (HCC), the...

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Dades bibliogràfiques
Publicat a:iScience
Autors principals: Kwon, So Mee, Lee, Young-Kyoung, Min, Seongki, Woo, Hyun Goo, Wang, Hee Jung, Yoon, Gyesoon
Format: Artigo
Idioma:Inglês
Publicat: Elsevier 2020
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7306587/
https://ncbi.nlm.nih.gov/pubmed/32629612
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.isci.2020.101247
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