Mitoribosome Defect in Hepatocellular Carcinoma Promotes an Aggressive Phenotype with Suppressed Immune Reaction

Mitochondrial ribosomes (mitoribosomes), the specialized translational machinery for mitochondrial genes, exclusively encode the subunits of the oxidative phosphorylation (OXPHOS) system. Although OXPHOS dysfunctions are associated with hepatic disorders including hepatocellular carcinoma (HCC), the...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:iScience
Prif Awduron: Kwon, So Mee, Lee, Young-Kyoung, Min, Seongki, Woo, Hyun Goo, Wang, Hee Jung, Yoon, Gyesoon
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Elsevier 2020
Pynciau:
Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC7306587/
https://ncbi.nlm.nih.gov/pubmed/32629612
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.isci.2020.101247
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