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Mitoribosome Defect in Hepatocellular Carcinoma Promotes an Aggressive Phenotype with Suppressed Immune Reaction

Mitochondrial ribosomes (mitoribosomes), the specialized translational machinery for mitochondrial genes, exclusively encode the subunits of the oxidative phosphorylation (OXPHOS) system. Although OXPHOS dysfunctions are associated with hepatic disorders including hepatocellular carcinoma (HCC), the...

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Detalhes bibliográficos
Publicado no:iScience
Main Authors: Kwon, So Mee, Lee, Young-Kyoung, Min, Seongki, Woo, Hyun Goo, Wang, Hee Jung, Yoon, Gyesoon
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7306587/
https://ncbi.nlm.nih.gov/pubmed/32629612
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.isci.2020.101247
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