T-Cell Epitopes and Neo-epitopes in Type 1 Diabetes: A Comprehensive Update and Reappraisal

The autoimmune disease type 1 diabetes is characterized by effector T-cell responses to pancreatic β-cell–derived peptides presented by HLA class I and class II molecules, leading ultimately to β-cell demise and insulin insufficiency. Although a given HLA molecule presents a vast array of peptides,...

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Bibliografiske detaljer
Udgivet i:Diabetes
Main Authors: James, Eddie A., Mallone, Roberto, Kent, Sally C., DiLorenzo, Teresa P.
Format: Artigo
Sprog:Inglês
Udgivet: American Diabetes Association 2020
Fag:
Perspectives in Diabetes
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7306130/
https://ncbi.nlm.nih.gov/pubmed/32561620
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2337/dbi19-0022
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