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Identification of Novel IGRP Epitopes Targeted in Type 1 Diabetes Patients

CD8(+) T cells play an important role in the development of type 1 diabetes (T1D) in NOD mice and humans. IGRP (islet-specific glucose-6-phosphatase catalytic subunit-related protein) has emerged in recent years as a major antigen in NOD mice. Therefore, we aimed to determine if IGRP is an antigen i...

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Detalhes bibliográficos
Main Authors: Jarchum, Irene, Nichol, Lynn, Trucco, Massimo, Santamaria, Pere, DiLorenzo, Teresa P.
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2430381/
https://ncbi.nlm.nih.gov/pubmed/18358785
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.clim.2008.01.015
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