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The Role of β Cell Stress and Neo-Epitopes in the Immunopathology of Type 1 Diabetes
Due to their secretory function, β cells are predisposed to higher levels of endoplasmic reticulum (ER) stress and greater sensitivity to inflammation than other cell types. These stresses elicit changes in β cells that alter their function and immunogenicity, including defective ribosomal initiatio...
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| Pubblicato in: | Front Endocrinol (Lausanne) |
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| Autori principali: | , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Frontiers Media S.A.
2021
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7930070/ https://ncbi.nlm.nih.gov/pubmed/33679609 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fendo.2020.624590 |
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