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The Evolving Landscape of Autoantigen Discovery and Characterization in Type 1 Diabetes

Type 1 diabetes (T1D) is an autoimmune disease that is caused, in part, by T cell–mediated destruction of insulin-producing β-cells. High risk for disease, in those with genetic susceptibility, is predicted by the presence of two or more autoantibodies against insulin, the 65-kDa form of glutamic ac...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Diabetes
Hauptverfasser: Purcell, Anthony W., Sechi, Salvatore, DiLorenzo, Teresa P.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Diabetes Association 2019
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6477901/
https://ncbi.nlm.nih.gov/pubmed/31010879
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2337/dbi18-0066
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