The secondary bile acids, ursodeoxycholic acid and lithocholic acid, protect against intestinal inflammation by inhibition of epithelial apoptosis

Increased epithelial permeability is a key feature of IBD pathogenesis and it has been proposed that agents which promote barrier function may be of therapeutic benefit. We have previously reported the secondary bile acid, ursodeoxycholic acid (UDCA), to be protective in a mouse model of colonic inf...

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Detalhes bibliográficos
Publicado no:Physiol Rep
Main Authors: Lajczak‐McGinley, Natalia K., Porru, Emanule, Fallon, Ciara M., Smyth, Jessica, Curley, Caitriona, McCarron, Paul A., Tambuwala, Murtaza M., Roda, Aldo, Keely, Stephen J.
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2020
Assuntos:
Original Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7305237/
https://ncbi.nlm.nih.gov/pubmed/32562381
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.14814/phy2.14456
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