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The secondary bile acids, ursodeoxycholic acid and lithocholic acid, protect against intestinal inflammation by inhibition of epithelial apoptosis

Increased epithelial permeability is a key feature of IBD pathogenesis and it has been proposed that agents which promote barrier function may be of therapeutic benefit. We have previously reported the secondary bile acid, ursodeoxycholic acid (UDCA), to be protective in a mouse model of colonic inf...

תיאור מלא

שמור ב:
מידע ביבליוגרפי
הוצא לאור ב:Physiol Rep
Main Authors: Lajczak‐McGinley, Natalia K., Porru, Emanule, Fallon, Ciara M., Smyth, Jessica, Curley, Caitriona, McCarron, Paul A., Tambuwala, Murtaza M., Roda, Aldo, Keely, Stephen J.
פורמט: Artigo
שפה:Inglês
יצא לאור: John Wiley and Sons Inc. 2020
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC7305237/
https://ncbi.nlm.nih.gov/pubmed/32562381
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.14814/phy2.14456
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