Ursodeoxycholic acid attenuates colonic epithelial secretory function

Dihydroxy bile acids, such as chenodeoxycholic acid (CDCA), are well known to promote colonic fluid and electrolyte secretion, thereby causing diarrhoea associated with bile acid malabsorption. However, CDCA is rapidly metabolised by colonic bacteria to ursodeoxycholic acid (UDCA), the effects of wh...

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Bibliografische gegevens
Hoofdauteurs: Kelly, Orlaith B, Mroz, Magdalena S, Ward, Joseph B J, Colliva, Carolina, Scharl, Michael, Pellicciari, Roberto, Gilmer, John F, Fallon, Padraic G, Hofmann, Alan F, Roda, Aldo, Murray, Frank E, Keely, Stephen J
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Blackwell Science Inc 2013
Onderwerpen:
Alimentary
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3650696/
https://ncbi.nlm.nih.gov/pubmed/23507881
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/jphysiol.2013.252544
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