Ursodeoxycholic acid attenuates colonic epithelial secretory function

Dihydroxy bile acids, such as chenodeoxycholic acid (CDCA), are well known to promote colonic fluid and electrolyte secretion, thereby causing diarrhoea associated with bile acid malabsorption. However, CDCA is rapidly metabolised by colonic bacteria to ursodeoxycholic acid (UDCA), the effects of wh...

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Detalhes bibliográficos
Main Authors: Kelly, Orlaith B, Mroz, Magdalena S, Ward, Joseph B J, Colliva, Carolina, Scharl, Michael, Pellicciari, Roberto, Gilmer, John F, Fallon, Padraic G, Hofmann, Alan F, Roda, Aldo, Murray, Frank E, Keely, Stephen J
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Science Inc 2013
Assuntos:
Alimentary
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3650696/
https://ncbi.nlm.nih.gov/pubmed/23507881
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/jphysiol.2013.252544
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