Ursodeoxycholic acid attenuates colonic epithelial secretory function

Dihydroxy bile acids, such as chenodeoxycholic acid (CDCA), are well known to promote colonic fluid and electrolyte secretion, thereby causing diarrhoea associated with bile acid malabsorption. However, CDCA is rapidly metabolised by colonic bacteria to ursodeoxycholic acid (UDCA), the effects of wh...

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Dettagli Bibliografici
Autori principali: Kelly, Orlaith B, Mroz, Magdalena S, Ward, Joseph B J, Colliva, Carolina, Scharl, Michael, Pellicciari, Roberto, Gilmer, John F, Fallon, Padraic G, Hofmann, Alan F, Roda, Aldo, Murray, Frank E, Keely, Stephen J
Natura: Artigo
Lingua:Inglês
Pubblicazione: Blackwell Science Inc 2013
Soggetti:
Alimentary
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3650696/
https://ncbi.nlm.nih.gov/pubmed/23507881
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/jphysiol.2013.252544
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