The secondary bile acids, ursodeoxycholic acid and lithocholic acid, protect against intestinal inflammation by inhibition of epithelial apoptosis

Increased epithelial permeability is a key feature of IBD pathogenesis and it has been proposed that agents which promote barrier function may be of therapeutic benefit. We have previously reported the secondary bile acid, ursodeoxycholic acid (UDCA), to be protective in a mouse model of colonic inf...

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Detalles Bibliográficos
Publicado en:Physiol Rep
Main Authors: Lajczak‐McGinley, Natalia K., Porru, Emanule, Fallon, Ciara M., Smyth, Jessica, Curley, Caitriona, McCarron, Paul A., Tambuwala, Murtaza M., Roda, Aldo, Keely, Stephen J.
Formato: Artigo
Idioma:Inglês
Publicado: John Wiley and Sons Inc. 2020
Assuntos:
Original Research
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC7305237/
https://ncbi.nlm.nih.gov/pubmed/32562381
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.14814/phy2.14456
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