Conditionally Controlling Human TLR2 Activity via Trans-Cyclooctene Caged Ligands

[Image: see text] Toll-like receptors (TLRs) are key pathogen sensors of the immune system. Their activation results in the production of cytokines, chemokines, and costimulatory molecules that are crucial for innate and adaptive immune responses. In recent years, specific (sub)-cellular location an...

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Detalles Bibliográficos
Publicado en:Bioconjug Chem
Main Authors: van de Graaff, Michel J., Oosenbrug, Timo, Marqvorsen, Mikkel H. S., Nascimento, Clarissa R., de Geus, Mark A. R., Manoury, Bénédicte, Ressing, Maaike E., van Kasteren, Sander I.
Formato: Artigo
Idioma:Inglês
Publicado: American Chemical Society 2020
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC7303972/
https://ncbi.nlm.nih.gov/pubmed/32510940
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.bioconjchem.0c00237
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