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Chemical Control over T-Cell Activation in Vivo Using Deprotection of trans-Cyclooctene-Modified Epitopes
[Image: see text] Activation of a cytotoxic T-cell is a complex multistep process, and tools to study the molecular events and their dynamics that result in T-cell activation in situ and in vivo are scarce. Here, we report the design and use of conditional epitopes for time-controlled T-cell activat...
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| Veröffentlicht in: | ACS Chem Biol |
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| Hauptverfasser: | , , , , , , , , , , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
American
Chemical Society
2018
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| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6006443/ https://ncbi.nlm.nih.gov/pubmed/29733186 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acschembio.8b00155 |
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