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Conditionally Controlling Human TLR2 Activity via Trans-Cyclooctene Caged Ligands

[Image: see text] Toll-like receptors (TLRs) are key pathogen sensors of the immune system. Their activation results in the production of cytokines, chemokines, and costimulatory molecules that are crucial for innate and adaptive immune responses. In recent years, specific (sub)-cellular location an...

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Detalhes bibliográficos
Publicado no:Bioconjug Chem
Main Authors: van de Graaff, Michel J., Oosenbrug, Timo, Marqvorsen, Mikkel H. S., Nascimento, Clarissa R., de Geus, Mark A. R., Manoury, Bénédicte, Ressing, Maaike E., van Kasteren, Sander I.
Formato: Artigo
Idioma:Inglês
Publicado em: American Chemical Society 2020
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7303972/
https://ncbi.nlm.nih.gov/pubmed/32510940
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.bioconjchem.0c00237
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