Genomic analysis of primary plasma cell leukemia reveals complex structural alterations and high-risk mutational patterns

Primary plasma cell leukemia (pPCL) is a rare and aggressive form of multiple myeloma (MM) that is characterized by the presence of ≥20% circulating plasma cells. Overall survival remains poor despite advances of anti-MM therapy. The disease biology as well as molecular mechanisms that distinguish p...

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Detalhes bibliográficos
Publicado no:Blood Cancer J
Main Authors: Schinke, Carolina, Boyle, Eileen M., Ashby, Cody, Wang, Yan, Lyzogubov, Valeriy, Wardell, Christopher, Qu, Pingping, Hoering, Antje, Deshpande, Shayu, Ryan, Katie, Thanendrarajan, Sharmilan, Mohan, Meera, Yarlagadda, Naveen, Khan, Maliha, Choudhury, Samrat Roy, Zangari, Maurizio, van Rhee, Frits, Davies, Faith, Barlogie, Bart, Morgan, Gareth, Walker, Brian A.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2020
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7303180/
https://ncbi.nlm.nih.gov/pubmed/32555163
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41408-020-0336-z
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