Evaluation of toxicity of aerosols from flavored e-liquids in Sprague–Dawley rats in a 90-day OECD inhalation study, complemented by transcriptomics analysis

The use of flavoring substances is an important element in the development of reduced-risk products for adult smokers to increase product acceptance and encourage switching from cigarettes. In a first step towards characterizing the sub-chronic inhalation toxicity of neat flavoring substances, a stu...

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Bibliographic Details
Published in:Arch Toxicol
Main Authors: Ho, Jenny, Sciuscio, Davide, Kogel, Ulrike, Titz, Bjoern, Leroy, Patrice, Vuillaume, Gregory, Talikka, Marja, Martin, Elyette, Pospisil, Pavel, Lebrun, Stefan, Xia, Wenhao, Lee, Tom, Chng, Yun Xuan, Phillips, Blaine W., Veljkovic, Emilija, Guedj, Emmanuel, Xiang, Yang, Ivanov, Nikolai V., Peitsch, Manuel C., Hoeng, Julia, Vanscheeuwijck, Patrick
Format: Artigo
Language:Inglês
Published: Springer Berlin Heidelberg 2020
Subjects:
Organ Toxicity and Mechanisms
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7303093/
https://ncbi.nlm.nih.gov/pubmed/32367274
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00204-020-02759-6
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