Effects of Cigarette Smoke, Cessation, and Switching to Two Heat-Not-Burn Tobacco Products on Lung Lipid Metabolism in C57BL/6 and Apoe(−/−) Mice—An Integrative Systems Toxicology Analysis

The impact of cigarette smoke (CS), a major cause of lung diseases, on the composition and metabolism of lung lipids is incompletely understood. Here, we integrated quantitative lipidomics and proteomics to investigate exposure effects on lung lipid metabolism in a C57BL/6 and an Apolipoprotein E-de...

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Publié dans:Toxicol Sci
Auteurs principaux: Titz, Bjoern, Boué, Stéphanie, Phillips, Blaine, Talikka, Marja, Vihervaara, Terhi, Schneider, Thomas, Nury, Catherine, Elamin, Ashraf, Guedj, Emmanuel, Peck, Michael J., Schlage, Walter K., Cabanski, Maciej, Leroy, Patrice, Vuillaume, Gregory, Martin, Florian, Ivanov, Nikolai V., Veljkovic, Emilija, Ekroos, Kim, Laaksonen, Reijo, Vanscheeuwijck, Patrick, Peitsch, Manuel C., Hoeng, Julia
Format: Artigo
Langue:Inglês
Publié: Oxford University Press 2016
Sujets:
Evaluation of Lung Lipid Toxicity of Non-Burn Tobacco Products
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4725611/
https://ncbi.nlm.nih.gov/pubmed/26582801
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/toxsci/kfv244
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