Semi-Automated Curation Allows Causal Network Model Building for the Quantification of Age-Dependent Plaque Progression in ApoE(−/−) Mouse

Por Szostak, Justyna, Martin, Florian, Talikka, Marja, Peitsch, Manuel C., Hoeng, Julia
Publicado no Gene Regul Syst Bio (2016)

Quantification of biological network perturbations for mechanistic insight and diagnostics using two-layer causal models

Por Martin, Florian, Sewer, Alain, Talikka, Marja, Xiang, Yang, Hoeng, Julia, Peitsch, Manuel C
Publicado no BMC Bioinformatics (2014)

Systems Approaches Evaluating the Perturbation of Xenobiotic Metabolism in Response to Cigarette Smoke Exposure in Nasal and Bronchial Tissues

Por Iskandar, Anita R., Martin, Florian, Talikka, Marja, Schlage, Walter K., Kostadinova, Radina, Mathis, Carole, Hoeng, Julia, Peitsch, Manuel C.
Publicado em 2013

Systems toxicology approaches enable mechanistic comparison of spontaneous and cigarette smoke-related lung tumor development in the A/J mouse model

Por Luettich, Karsta, Xiang, Yang, Iskandar, Anita, Sewer, Alain, Martin, Florian, Talikka, Marja, Vanscheeuwijck, Patrick, Berges, An, Veljkovic, Emilija, Gonzalez-Suarez, Ignacio, Schlage, Walter, Hoeng, Julia, Peitsch, Manuel
Publicado no Interdiscip Toxicol (2014)

Impact Assessment of Cigarette Smoke Exposure on Organotypic Bronchial Epithelial Tissue Cultures: A Comparison of Mono-Culture and Coculture Model Containing Fibroblasts

Por Iskandar, Anita R., Xiang, Yang, Frentzel, Stefan, Talikka, Marja, Leroy, Patrice, Kuehn, Diana, Guedj, Emmanuel, Martin, Florian, Mathis, Carole, Ivanov, Nikolai V., Peitsch, Manuel C., Hoeng, Julia
Publicado no Toxicol Sci (2015)

In vitro systems toxicology approach to investigate the effects of repeated cigarette smoke exposure on human buccal and gingival organotypic epithelial tissue cultures

Por Schlage, Walter K., Iskandar, Anita R., Kostadinova, Radina, Xiang, Yang, Sewer, Alain, Majeed, Shoaib, Kuehn, Diana, Frentzel, Stefan, Talikka, Marja, Geertz, Marcel, Mathis, Carole, Ivanov, Nikolai, Hoeng, Julia, Peitsch, Manuel C.
Publicado no Toxicol Mech Methods (2014)

Construction of a Computable Network Model for DNA Damage, Autophagy, Cell Death, and Senescence

Por Gebel, Stephan, Lichtner, Rosemarie B., Frushour, Brian, Schlage, Walter K., Hoang, Vy, Talikka, Marja, Hengstermann, Arnd, Mathis, Carole, Veljkovic, Emilija, Peck, Michael, Peitsch, Manuel C., Deehan, Renee, Hoeng, Julia, Westra, Jurjen W.
Publicado em 2013

Causal biological network database: a comprehensive platform of causal biological network models focused on the pulmonary and vascular systems

Por Boué, Stéphanie, Talikka, Marja, Westra, Jurjen Willem, Hayes, William, Di Fabio, Anselmo, Park, Jennifer, Schlage, Walter K., Sewer, Alain, Fields, Brett, Ansari, Sam, Martin, Florian, Veljkovic, Emilija, Kenney, Renee, Peitsch, Manuel C., Hoeng, Julia
Publicado no Database (Oxford) (2015)

A Modular Cell-Type Focused Inflammatory Process Network Model for Non-Diseased Pulmonary Tissue

Por Westra, Jurjen W., Schlage, Walter K., Hengstermann, Arnd, Gebel, Stephan, Mathis, Carole, Thomson, Ty, Wong, Ben, Hoang, Vy, Veljkovic, Emilija, Peck, Michael, Lichtner, Rosemarie B., Weisensee, Dirk, Talikka, Marja, Deehan, Renee, Hoeng, Julia, Peitsch, Manuel C.
Publicado em 2013

On Crowd-verification of Biological Networks

Por Ansari, Sam, Binder, Jean, Boue, Stephanie, Di Fabio, Anselmo, Hayes, William, Hoeng, Julia, Iskandar, Anita, Kleiman, Robin, Norel, Raquel, O’Neel, Bruce, Peitsch, Manuel C., Poussin, Carine, Pratt, Dexter, Rhrissorrakrai, Kahn, Schlage, Walter K., Stolovitzky, Gustavo, Talikka, Marja
Publicado em 2013

Strengths and limitations of microarray-based phenotype prediction: lessons learned from the IMPROVER Diagnostic Signature Challenge

Por Tarca, Adi L., Lauria, Mario, Unger, Michael, Bilal, Erhan, Boue, Stephanie, Kumar Dey, Kushal, Hoeng, Julia, Koeppl, Heinz, Martin, Florian, Meyer, Pablo, Nandy, Preetam, Norel, Raquel, Peitsch, Manuel, Rice, Jeremy J., Romero, Roberto, Stolovitzky, Gustavo, Talikka, Marja, Xiang, Yang, Zechner, Christoph
Publicado em 2013

Transcriptional profiling and targeted proteomics reveals common molecular changes associated with cigarette smoke-induced lung emphysema development in five susceptible mouse stra...

Por Cabanski, Maciej, Fields, Brett, Boue, Stephanie, Boukharov, Natalia, DeLeon, Hector, Dror, Natalie, Geertz, Marcel, Guedj, Emmanuel, Iskandar, Anita, Kogel, Ulrike, Merg, Celine, Peck, Michael J., Poussin, Carine, Schlage, Walter K., Talikka, Marja, Ivanov, Nikolai V., Hoeng, Julia, Peitsch, Manuel C.
Publicado no Inflamm Res (2015)

A vascular biology network model focused on inflammatory processes to investigate atherogenesis and plaque instability

Por De León, Héctor, Boué, Stéphanie, Schlage, Walter K, Boukharov, Natalia, Westra, Jurjen W, Gebel, Stephan, VanHooser, Aaron, Talikka, Marja, Fields, R Brett, Veljkovic, Emilija, Peck, Michael J, Mathis, Carole, Hoang, Vy, Poussin, Carine, Deehan, Renee, Stolle, Katrin, Hoeng, Julia, Peitsch, Manuel C
Publicado no J Transl Med (2014)

An 8-Month Systems Toxicology Inhalation/Cessation Study in Apoe(−/−) Mice to Investigate Cardiovascular and Respiratory Exposure Effects of a Candidate Modified Risk Tobacco Produ...

Por Phillips, Blaine, Veljkovic, Emilija, Boué, Stéphanie, Schlage, Walter K., Vuillaume, Gregory, Martin, Florian, Titz, Bjoern, Leroy, Patrice, Buettner, Ansgar, Elamin, Ashraf, Oviedo, Alberto, Cabanski, Maciej, De León, Héctor, Guedj, Emmanuel, Schneider, Thomas, Talikka, Marja, Ivanov, Nikolai V., Vanscheeuwijck, Patrick, Peitsch, Manuel C., Hoeng, Julia
Publicado no Toxicol Sci (2016)

The species translation challenge—A systems biology perspective on human and rat bronchial epithelial cells

Por Poussin, Carine, Mathis, Carole, Alexopoulos, Leonidas G, Messinis, Dimitris E, Dulize, Rémi H J, Belcastro, Vincenzo, Melas, Ioannis N, Sakellaropoulos, Theodore, Rhrissorrakrai, Kahn, Bilal, Erhan, Meyer, Pablo, Talikka, Marja, Boué, Stéphanie, Norel, Raquel, Rice, John J, Stolovitzky, Gustavo, Ivanov, Nikolai V, Peitsch, Manuel C, Hoeng, Julia
Publicado no Sci Data (2014)

Effects of Cigarette Smoke, Cessation, and Switching to Two Heat-Not-Burn Tobacco Products on Lung Lipid Metabolism in C57BL/6 and Apoe(−/−) Mice—An Integrative Systems Toxicology...

Por Titz, Bjoern, Boué, Stéphanie, Phillips, Blaine, Talikka, Marja, Vihervaara, Terhi, Schneider, Thomas, Nury, Catherine, Elamin, Ashraf, Guedj, Emmanuel, Peck, Michael J., Schlage, Walter K., Cabanski, Maciej, Leroy, Patrice, Vuillaume, Gregory, Martin, Florian, Ivanov, Nikolai V., Veljkovic, Emilija, Ekroos, Kim, Laaksonen, Reijo, Vanscheeuwijck, Patrick, Peitsch, Manuel C., Hoeng, Julia
Publicado no Toxicol Sci (2016)

Construction of a computable cell proliferation network focused on non-diseased lung cells

Por Westra, Jurjen W, Schlage, Walter K, Frushour, Brian P, Gebel, Stephan, Catlett, Natalie L, Han, Wanjiang, Eddy, Sean F, Hengstermann, Arnd, Matthews, Andrea L, Mathis, Carole, Lichtner, Rosemarie B, Poussin, Carine, Talikka, Marja, Veljkovic, Emilija, Van Hooser, Aaron A, Wong, Benjamin, Maria, Michael J, Peitsch, Manuel C, Deehan, Renee, Hoeng, Julia
Publicado em 2011

Comprehensive systems biology analysis of a 7-month cigarette smoke inhalation study in C57BL/6 mice

Por Ansari, Sam, Baumer, Karine, Boué, Stéphanie, Dijon, Sophie, Dulize, Remi, Ekroos, Kim, Elamin, Ashraf, Foong, Clement, Guedj, Emmanuel, Hoeng, Julia, Ivanov, Nikolai V., Krishnan, Subash, Leroy, Patrice, Martin, Florian, Merg, Celine, Peck, Michael J., Peitsch, Manuel C., Phillips, Blaine, Schlage, Walter K., Schneider, Thomas, Talikka, Marja, Titz, Bjoern, Vanscheeuwijck, Patrick, Veljkovic, Emilija, Vihervaara, Terhi, Vuillaume, Gregory, Woon, Ching Qing
Publicado no Sci Data (2016)

Enhancement of COPD biological networks using a web-based collaboration interface

Por Boue, Stephanie, Fields, Brett, Hoeng, Julia, Park, Jennifer, Peitsch, Manuel C., Schlage, Walter K., Talikka, Marja, Binenbaum, Ilona, Bondarenko, Vladimir, Bulgakov, Oleg V., Cherkasova, Vera, Diaz-Diaz, Norberto, Fedorova, Larisa, Guryanova, Svetlana, Guzova, Julia, Igorevna Koroleva, Galina, Kozhemyakina, Elena, Kumar, Rahul, Lavid, Noa, Lu, Qingxian, Menon, Swapna, Ouliel, Yael, Peterson, Samantha C., Prokhorov, Alexander, Sanders, Edward, Schrier, Sarah, Schwaitzer Neta, Golan, Shvydchenko, Irina, Tallam, Aravind, Villa-Fombuena, Gema, Wu, John, Yudkevich, Ilya, Zelikman, Mariya
Publicado no F1000Res (2015)

Community-Reviewed Biological Network Models for Toxicology and Drug Discovery Applications

Por Namasivayam, Aishwarya Alex, Morales, Alejandro Ferreiro, Lacave, Ángela María Fajardo, Tallam, Aravind, Simovic, Borislav, Alfaro, David Garrido, Bobbili, Dheeraj Reddy, Martin, Florian, Androsova, Ganna, Shvydchenko, Irina, Park, Jennifer, Calvo, Jorge Val, Hoeng, Julia, Peitsch, Manuel C., Racero, Manuel González Vélez, Biryukov, Maria, Talikka, Marja, Pérez, Modesto Berraquero, Rohatgi, Neha, Díaz-Díaz, Noberto, Mandarapu, Rajesh, Ruiz, Rubén Amián, Davidyan, Sergey, Narayanasamy, Shaman, Boué, Stéphanie, Guryanova, Svetlana, Arbas, Susana Martínez, Menon, Swapna, Xiang, Yang
Publicado no Gene Regul Syst Bio (2016)