Small proline‐rich repeat 3 is a novel coordinator of PDGFRβ and integrin β1 crosstalk to augment proliferation and matrix synthesis by cardiac fibroblasts

Nearly 6 million Americans suffer from heart failure. Increased fibrosis contributes to functional decline of the heart that leads to heart failure. Previously, we identified a mechanosensitive protein, small proline‐rich repeat 3 (SPRR3), in vascular smooth muscle cells of atheromas. In this study,...

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Vydáno v:FASEB J
Hlavní autoři: Saraswati, Sarika, Lietman, Caressa D., Li, Bin, Mathew, Sijo, Zent, Roy, Young, Pampee P.
Médium: Artigo
Jazyk:Inglês
Vydáno: John Wiley and Sons Inc. 2020
Témata:
Research Articles
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7302973/
https://ncbi.nlm.nih.gov/pubmed/32297675
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fj.201902815R
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