Lung cancer models reveal SARS-CoV-2-induced EMT contributes to COVID-19 pathophysiology

COVID-19 is an infectious disease caused by SARS-CoV-2, which enters host cells via the cell surface proteins ACE2 and TMPRSS2. Using a variety of normal and malignant models and tissues from the aerodigestive and respiratory tracts, we investigated the expression and regulation of ACE2 and TMPRSS2....

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Publicado no:bioRxiv
Main Authors: Stewart, C. Allison, Gay, Carl M., Ramkumar, Kavya, Cargill, Kasey R., Cardnell, Robert J., Nilsson, Monique B., Heeke, Simon, Park, Elizabeth M., Kundu, Samrat T., Diao, Lixia, Wang, Qi, Shen, Li, Xi, Yuanxin, Zhang, Bingnan, Della Corte, Carminia Maria, Fan, Youhong, Kundu, Kiran, Gao, Boning, Avila, Kimberley, Pickering, Curtis R., Johnson, Faye M., Zhang, Jianjun, Kadara, Humam, Minna, John D., Gibbons, Don L., Wang, Jing, Heymach, John V., Byers, Lauren Averett
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory 2021
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7302206/
https://ncbi.nlm.nih.gov/pubmed/32577652
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/2020.05.28.122291
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