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The utility of native MS for understanding the mechanism of action of repurposed therapeutics in COVID-19: heparin as a disruptor of the SARS-CoV-2 interaction with its host cell receptor

The emergence and rapid proliferation of the novel coronavirus (SARS-CoV-2) resulted in a global pandemic, with over six million cases and nearly four hundred thousand deaths reported world-wide by the end of May 2020. A rush to find the cures prompted re-evaluation of a range of existing therapeuti...

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Publicat a:bioRxiv
Autors principals: Yang, Yang, Du, Yi, Kaltashov, Igor A.
Format: Artigo
Idioma:Inglês
Publicat: Cold Spring Harbor Laboratory 2020
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7302200/
https://ncbi.nlm.nih.gov/pubmed/32577646
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/2020.06.09.142794
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