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The challenge of structural heterogeneity in the native mass spectrometry studies of the SARS-CoV-2 spike protein interactions with its host cell-surface receptor

Native mass spectrometry (MS) enjoyed tremendous success in the past two decades in a wide range of studies aiming at understanding the molecular mechanisms of physiological processes underlying a variety of pathologies and accelerating the drug discovery process. However, the success record of nati...

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Detalles Bibliográficos
Publicado en:bioRxiv
Main Authors: Yang, Yang, Ivanov, Daniil G., Kaltashov, Igor A.
Formato: Artigo
Idioma:Inglês
Publicado: Cold Spring Harbor Laboratory 2021
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC8240678/
https://ncbi.nlm.nih.gov/pubmed/34189525
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/2021.06.20.449191
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