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The utility of native MS for understanding the mechanism of action of repurposed therapeutics in COVID-19: heparin as a disruptor of the SARS-CoV-2 interaction with its host cell receptor

The emergence and rapid proliferation of the novel coronavirus (SARS-CoV-2) resulted in a global pandemic, with over six million cases and nearly four hundred thousand deaths reported worldwide by the end of May 2020. A rush to find the cure prompted re-evaluation of a range of existing therapeutics...

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Detalhes bibliográficos
Publicado no:Anal Chem
Main Authors: Yang, Yang, Du, Yi, Kaltashov, Igor A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7384394/
https://ncbi.nlm.nih.gov/pubmed/32678978
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.analchem.0c02449
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