Structural basis of a public antibody response to SARS-CoV-2

Molecular-level understanding of human neutralizing antibody responses to SARS-CoV-2 could accelerate vaccine design and facilitate drug discovery. We analyzed 294 SARS-CoV-2 antibodies and found that IGHV3–53 is the most frequently used IGHV gene for targeting the receptor binding domain (RBD) of t...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:bioRxiv
Main Authors: Yuan, Meng, Liu, Hejun, Wu, Nicholas C., Lee, Chang-Chun D., Zhu, Xueyong, Zhao, Fangzhu, Huang, Deli, Yu, Wenli, Hua, Yuanzi, Tien, Henry, Rogers, Thomas F., Landais, Elise, Sok, Devin, Jardine, Joseph G., Burton, Dennis R., Wilson, Ian A.
Format: Artigo
Jezik:Inglês
Izdano: Cold Spring Harbor Laboratory 2020
Teme:
Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC7302194/
https://ncbi.nlm.nih.gov/pubmed/32577642
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/2020.06.08.141267
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