Structural basis of a shared antibody response to SARS-CoV-2

Molecular understanding of neutralizing antibody responses to severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) could accelerate vaccine design and drug discovery. We analyzed 294 anti–SARS-CoV-2 antibodies and found that immunoglobulin G heavy-chain variable region 3-53 (IGHV3-53) is the...

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Pubblicato in:Science
Autori principali: Yuan, Meng, Liu, Hejun, Wu, Nicholas C., Lee, Chang-Chun D., Zhu, Xueyong, Zhao, Fangzhu, Huang, Deli, Yu, Wenli, Hua, Yuanzi, Tien, Henry, Rogers, Thomas F., Landais, Elise, Sok, Devin, Jardine, Joseph G., Burton, Dennis R., Wilson, Ian A.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Association for the Advancement of Science 2020
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Reports
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7402627/
https://ncbi.nlm.nih.gov/pubmed/32661058
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.abd2321
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