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TUMOR CELL-DERIVED IL-1β PROMOTES DESMOPLASIA AND IMMUNE SUPPRESSION IN PANCREATIC CANCER
Pancreatic ductal adenocarcinoma (PDA) is an aggressive malignancy typified by a highly stromal and weakly immunogenic tumor microenvironment that promotes tumor evolution and contributes to therapeutic resistance. Here, we demonstrate that PDA tumor cell-derived pro-inflammatory cytokine, interleuk...
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| Publicado no: | Cancer Res |
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| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7302116/ https://ncbi.nlm.nih.gov/pubmed/31915130 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-19-2080 |
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