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BTK SIGNALING DRIVES CD1d(hi)CD5(+) REGULATORY B CELL DIFFERENTIATION TO PROMOTE PANCREATIC CARCINOGENESIS
The immune microenvironment of pancreatic ductal adenocarcinoma (PDAC) is comprised of a heterogeneous population of cells that are critical for disease evolution. Prominent among these are the specialized CD1d(hi)CD5(+) regulatory B (B(reg)) cells that exert a pro-tumorigenic role by promoting tumo...
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| Publicado no: | Oncogene |
|---|---|
| Main Authors: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6486434/ https://ncbi.nlm.nih.gov/pubmed/30635655 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41388-018-0668-3 |
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