Epigenetic silencing of AATK in acinar to ductal metaplasia in murine model of pancreatic cancer

BACKGROUND: Cancer subtype switching, which involves unclear cancer cell origin, cell fate decision, and transdifferentiation of cells within a confined tumor microenvironment, remains a major problem in pancreatic cancer (PDA). RESULTS: By analyzing PDA subtypes in The Cancer Genome Atlas, we ident...

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Publicado en:Clin Epigenetics
Autores principales: Ding, Li-Yun, Hou, Ya-Chin, Kuo, I-Ying, Hsu, Ting-Yi, Tsai, Tsung-Ching, Chang, Hsiu-Wei, Hsu, Wei-Yu, Tsao, Chih-Chieh, Tian, Chung-Chen, Wang, Po-Shun, Wang, Hao-Chen, Lee, Chung-Ta, Wang, Yi-Ching, Lin, Sheng-Hsiang, Hughes, Michael W., Chuang, Woei-Jer, Lu, Pei-Jung, Shan, Yan-Shen, Huang, Po-Hsien
Formato: Artigo
Lenguaje:Inglês
Publicado: BioMed Central 2020
Materias:
Research
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC7301993/
https://ncbi.nlm.nih.gov/pubmed/32552862
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13148-020-00878-6
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