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Deferoxamine deconditioning increases neuronal vulnerability to hemoglobin

Concomitant treatment with deferoxamine (DFO) protects neural cells from iron and heme-mediated oxidative injury, but also disrupts cell responses to iron loading that may be protective. We hypothesized that DFO treatment and withdrawal would subsequently increase neuronal vulnerability to hemoglobi...

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Bibliografiske detaljer
Udgivet i:Exp Cell Res
Main Authors: Peng, Denggao, Chen, Cindy Acon, Ruhela, Deepa, Li, Yang, Regan, Raymond F.
Format: Artigo
Sprog:Inglês
Udgivet: 2020
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7301423/
https://ncbi.nlm.nih.gov/pubmed/32112801
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.yexcr.2020.111926
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