A Novel Organoid Model of Damage and Repair Identifies HNF4α as a Critical Regulator of Intestinal Epithelial Regeneration

BACKGROUND & AIMS: Recent evidence has suggested that the intact intestinal epithelial barrier protects our body from a range of immune-mediated diseases. The epithelial layer has an impressive ability to reconstitute and repair upon damage and this process of repair increasingly is seen as a th...

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Detalles Bibliográficos
Publicado en:Cell Mol Gastroenterol Hepatol
Autores principales: Montenegro-Miranda, Paula S., van der Meer, Jonathan H.M., Jones, Christine, Meisner, Sander, Vermeulen, Jacqueline L.M., Koster, Jan, Wildenberg, Manon E., Heijmans, Jarom, Boudreau, Francois, Ribeiro, Agnes, van den Brink, Gijs R., Muncan, Vanesa
Formato: Artigo
Lenguaje:Inglês
Publicado: Elsevier 2020
Materias:
Original Research
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC7301200/
https://ncbi.nlm.nih.gov/pubmed/32145468
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jcmgh.2020.02.007
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