A Novel Organoid Model of Damage and Repair Identifies HNF4α as a Critical Regulator of Intestinal Epithelial Regeneration

BACKGROUND & AIMS: Recent evidence has suggested that the intact intestinal epithelial barrier protects our body from a range of immune-mediated diseases. The epithelial layer has an impressive ability to reconstitute and repair upon damage and this process of repair increasingly is seen as a th...

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Bibliografski detalji
Izdano u:Cell Mol Gastroenterol Hepatol
Glavni autori: Montenegro-Miranda, Paula S., van der Meer, Jonathan H.M., Jones, Christine, Meisner, Sander, Vermeulen, Jacqueline L.M., Koster, Jan, Wildenberg, Manon E., Heijmans, Jarom, Boudreau, Francois, Ribeiro, Agnes, van den Brink, Gijs R., Muncan, Vanesa
Format: Artigo
Jezik:Inglês
Izdano: Elsevier 2020
Teme:
Original Research
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7301200/
https://ncbi.nlm.nih.gov/pubmed/32145468
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jcmgh.2020.02.007
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