A Novel Organoid Model of Damage and Repair Identifies HNF4α as a Critical Regulator of Intestinal Epithelial Regeneration

BACKGROUND & AIMS: Recent evidence has suggested that the intact intestinal epithelial barrier protects our body from a range of immune-mediated diseases. The epithelial layer has an impressive ability to reconstitute and repair upon damage and this process of repair increasingly is seen as a th...

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Detalhes bibliográficos
Publicado no:Cell Mol Gastroenterol Hepatol
Main Authors: Montenegro-Miranda, Paula S., van der Meer, Jonathan H.M., Jones, Christine, Meisner, Sander, Vermeulen, Jacqueline L.M., Koster, Jan, Wildenberg, Manon E., Heijmans, Jarom, Boudreau, Francois, Ribeiro, Agnes, van den Brink, Gijs R., Muncan, Vanesa
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2020
Assuntos:
Original Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7301200/
https://ncbi.nlm.nih.gov/pubmed/32145468
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jcmgh.2020.02.007
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