Rewiring of glucose metabolism defines trained immunity induced by oxidized low-density lipoprotein

ABSTRACT: Stimulation of monocytes with microbial and non-microbial products, including oxidized low-density lipoprotein (oxLDL), induces a protracted pro-inflammatory, atherogenic phenotype sustained by metabolic and epigenetic reprogramming via a process called trained immunity. We investigated th...

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Vydáno v:J Mol Med (Berl)
Hlavní autoři: Keating, Samuel T., Groh, Laszlo, Thiem, Kathrin, Bekkering, Siroon, Li, Yang, Matzaraki, Vasiliki, van der Heijden, Charlotte D. C. C., van Puffelen, Jelmer H., Lachmandas, Ekta, Jansen, Trees, Oosting, Marije, de Bree, L. Charlotte J., Koeken, Valerie A. C. M., Moorlag, Simone J. C. F. M., Mourits, Vera P., van Diepen, Janna, Strienstra, Rinke, Novakovic, Boris, Stunnenberg, Hendrik G., van Crevel, Reinout, Joosten, Leo A. B., Netea, Mihai G., Riksen, Niels P.
Médium: Artigo
Jazyk:Inglês
Vydáno: Springer Berlin Heidelberg 2020
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Original Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7297856/
https://ncbi.nlm.nih.gov/pubmed/32350546
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00109-020-01915-w
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