Rewiring of glucose metabolism defines trained immunity induced by oxidized low-density lipoprotein

ABSTRACT: Stimulation of monocytes with microbial and non-microbial products, including oxidized low-density lipoprotein (oxLDL), induces a protracted pro-inflammatory, atherogenic phenotype sustained by metabolic and epigenetic reprogramming via a process called trained immunity. We investigated th...

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Библиографические подробности
Опубликовано в: :J Mol Med (Berl)
Главные авторы: Keating, Samuel T., Groh, Laszlo, Thiem, Kathrin, Bekkering, Siroon, Li, Yang, Matzaraki, Vasiliki, van der Heijden, Charlotte D. C. C., van Puffelen, Jelmer H., Lachmandas, Ekta, Jansen, Trees, Oosting, Marije, de Bree, L. Charlotte J., Koeken, Valerie A. C. M., Moorlag, Simone J. C. F. M., Mourits, Vera P., van Diepen, Janna, Strienstra, Rinke, Novakovic, Boris, Stunnenberg, Hendrik G., van Crevel, Reinout, Joosten, Leo A. B., Netea, Mihai G., Riksen, Niels P.
Формат: Artigo
Язык:Inglês
Опубликовано: Springer Berlin Heidelberg 2020
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Original Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC7297856/
https://ncbi.nlm.nih.gov/pubmed/32350546
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00109-020-01915-w
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