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Strand with mutagenic lesion is preferentially used as a template in the region of a bi-stranded clustered DNA damage site in Escherichia coli

The damaging potential of ionizing radiation arises largely from the generation of clustered DNA damage sites within cells. Previous studies using synthetic DNA lesions have demonstrated that models of clustered DNA damage exhibit enhanced mutagenic potential of the comprising lesions. However, litt...

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Bibliografiske detaljer
Udgivet i:Sci Rep
Main Authors: Shikazono, Naoya, Akamatsu, Ken
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group UK 2020
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7297740/
https://ncbi.nlm.nih.gov/pubmed/32546758
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-66651-0
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