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Processing of thymine glycol in a clustered DNA damage site: mutagenic or cytotoxic
Localized clustering of damage is a hallmark of certain DNA-damaging agents, particularly ionizing radiation. The potential for genetic change arising from the effects of clustered damage sites containing combinations of AP sites, 8-oxo-7,8-dihydroguanine (8-oxoG) or 5,6-dihydrothymine is high. To d...
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| Autori principali: | , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Oxford University Press
2009
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2715253/ https://ncbi.nlm.nih.gov/pubmed/19468043 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkp422 |
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