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The roles of specific glycosylases in determining the mutagenic consequences of clustered DNA base damage

The potential for genetic change arising from specific single types of DNA lesion has been thoroughly explored, but much less is known about the mutagenic effects of DNA lesions present in clustered damage sites. Localized clustering of damage is a hallmark of certain DNA-damaging agents, particular...

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Detalhes bibliográficos
Main Authors: Shikazono, Naoya, Pearson, Colin, O'Neill, Peter, Thacker, John
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2006
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1557791/
https://ncbi.nlm.nih.gov/pubmed/16893955
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkl503
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