Increased mutability and decreased repairability of a three-lesion clustered DNA-damaged site comprised of an AP site and bi-stranded 8-oxoG lesions

Lignende værker

• Reduced repair capacity of a DNA clustered damage site comprised of 8-oxo-7,8-dihydro-2′-deoxyguanosine and 2-deoxyribonolactone results in an increased mutagenic potential of these lesions
  af: Cunniffe, Siobhan, et al.
  Udgivet: (2014)
• Hierarchy of lesion processing governs the repair, double-strand break formation and mutability of three-lesion clustered DNA damage
  af: Eccles, Laura J., et al.
  Udgivet: (2010)
• Base excision repair processing of abasic site/single-strand break lesions within clustered damage sites associated with XRCC1 deficiency
  af: Mourgues, Sophie, et al.
  Udgivet: (2007)
• Processing of thymine glycol in a clustered DNA damage site: mutagenic or cytotoxic
  af: Bellon, Sophie, et al.
  Udgivet: (2009)
• Efficient cleavage of single and clustered AP site lesions within mono-nucleosome templates by CHO-K1 nuclear extract contrasts with retardation of incision by purified APE1
  af: Eccles, Laura J., et al.
  Udgivet: (2015)