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Inhibition of 5-lipoxygenase derived leukotrienes and hemiketals as a novel anti-inflammatory mechanism of urolithins

SCOPE: Urolithins, gut microbial metabolites derived from ellagic acid (EA), reach significant concentrations in the human colon. Urolithin-A (Uro-A) exerts anti-inflammatory activity in animal models of inflammatory bowel diseases (IBDs). We hypothesized that urolithins could modulate the biosynthe...

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Bibliografiske detaljer
Udgivet i:Mol Nutr Food Res
Main Authors: Giménez-Bastida, Juan Antonio, González-Sarrías, Antonio, Espín, Juan Carlos, Schneider, Claus
Format: Artigo
Sprog:Inglês
Udgivet: 2020
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7297467/
https://ncbi.nlm.nih.gov/pubmed/32306507
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/mnfr.202000129
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