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Inhibition of 5-lipoxygenase derived leukotrienes and hemiketals as a novel anti-inflammatory mechanism of urolithins
SCOPE: Urolithins, gut microbial metabolites derived from ellagic acid (EA), reach significant concentrations in the human colon. Urolithin-A (Uro-A) exerts anti-inflammatory activity in animal models of inflammatory bowel diseases (IBDs). We hypothesized that urolithins could modulate the biosynthe...
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| Publié dans: | Mol Nutr Food Res |
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| Auteurs principaux: | , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
2020
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7297467/ https://ncbi.nlm.nih.gov/pubmed/32306507 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/mnfr.202000129 |
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